Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms.

Acta Neuropathol · 2019 · PMC6531424 · PMID 30788585

Europe PMC DOI

hedged sentences

0.0529

closest p · 1.1× alpha

0.0529

boldest claim

The sentences

a strong trendp = 0.0529so close (0.05 < p ≤ 0.1)

In the hippocampus, WT mice injected with HTTExon1Q48 depicted a strong trend towards a decrease compared to HTTExon1Q25-treated mice ( p = 0.0529) (Online Resource 6b and c), while R6/2 mice injected with HTTExon1Q48 displayed a significant reduction in signal intensity compared to BSA treated mice and a strong trend towards a decrease compared to Q25-treated mice ( p = 0.0586) in the hippocampus (Online Resource 6c).

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showed a trendno p-value reported

4 f), although the more posterior cortical regions also showed a trend towards a decrease (data not shown).

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