Characterization of Vitamin B12 Supplementation and Correlation with Clinical Outcomes in a Large Longitudinal Study of Early Parkinson's Disease.

J Mov Disord · 2019 · PMC6547038 · PMID 31158942

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showed a trendno p-value reported

Other outcomes, such as the development of freezing, showed a trend toward a lower rate of 13.2% for the B12 + MVI group compared to the NoB12Supp group rate of 22.4%, but this lower rate was not observed in the B12 group, which had a rate of 34.6%.

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did not reach statistical significanceno p-value reported

The reason why the B12 group did not reach statistical significance, while the MVI + B12 group did, could reflect the benefit of the additional amount of B12 in the MVI in the MVI + B12 group versus the benefit of other nutrients in the MVI, such as folate or vitamin B6.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.