Barely Significant
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Characterizing Fatigue-Related White Matter Changes in MS: A Proton Magnetic Resonance Spectroscopy Study.

Brain Sci · 2019 · PMC6562940 · PMID 31137831

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Although the decline in the (NAA+NAAG)/(Cr+PCr) ratio in bilateral posterior quadrants did not reach statistical significance, the (NAA+NAAG)/(Cr+PCr) ratio variation in bilateral posterior quadrants is negative and significantly different in the HF group compared with the LF group.

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showed a trendno p-value reported
Interestingly, the HF group showed a trend toward a decline in fatigue scores at year 1.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.