Inter-Individual Variability in Xenobiotic-Metabolizing Enzymes: Implications for Human Aging and Longevity.

Genes (Basel) · 2019 · PMC6562959 · PMID 31137904

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0540

boldest claim

The sentences

nominally significantp -value < 0.05actually significant

Four SNPs demonstrated a nominally significant association ( p -value < 0.05) in at least one comparison (see Table 2 ).

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a trend toward significancep -value = 0.054so close (0.05 < p ≤ 0.1)

In this last case, however, only a trend toward significance was detected (OR = 1.66 CI 95% 0.99–2.79; p -value = 0.054) ( Table 2 and Figure 1 B).

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showed a trendp -value = 0.054so close (0.05 < p ≤ 0.1)

Kaplan–Meier survival analysis showed a trend for a positive association with survival for carriers of the minor allele (A) of rs2273697 in ABCC2 ( p -value = 0.054; see Figure 2 ), a result consistent with the positive effect on longevity.

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