Questionable Efficacy of Therapeutic Antibodies in the Treatment of Anthrax.

However, the difference in survival rate between the two groups did not reach statistical significance ( P = 0.0874), ruling out a benefit of the combination upon the employment of proper statistical standards, although the authors claimed a “higher survival rate” ( 22 ).

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The choice of PA as a unique therapeutic target was not questioned until a recent meta-analysis of nine studies including 4 species and 748 animals revealed that all but one study failed to reach statistical significance ( 5 ).

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