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Increased cerebral vascularization and decreased water exchange across the blood-brain barrier in aquaporin-4 knockout mice.

PLoS One · 2019 · PMC6586297 · PMID 31220136

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showed a trendno p-value reported
AQP4-KO mice also showed a trend of reduced peak 17 O signal in CSF.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.