HPV vaccination has not increased sexual activity or accelerated sexual debut in a college-aged cohort of men and women.

Increased likelihood of sexual debut was associated with age and reporting current alcohol use; being white approached significance.

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Statistical significance is reported at level α = 0.05; associations in the multivariate models with p -values less than α = 0.1 are noted as approaching significance to avoid overlooking associations that were not significant because of limited sample size.

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