Efficacy and Limitations of rCBF-SPECT in the Diagnosis of Alzheimer's Disease With Amyloid-PET.

Am J Alzheimers Dis Other Demen · 2019 · PMC6610554 · PMID 30966759

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difference was apparentno p-value reported

No significant difference was apparent in the MMSE score among the 3 groups (“unlikely”, “likely,” and “very likely”) defined by rCBF-SPECT ( Figure 6 ).

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weakly significantno p-value reported

The rCBF-PET using 15 O-CO 2 inhalation steady state method demonstrated that superofrontal gyrus was identified with weakly significant linear decreases with advancing age. 26 The other study using 15 O-H 2 O intravenous bolus injection method revealed that the mean cortical CBF, and rCBF of lateral temporal and lateral orbitofrontal were lower in the elderly group (older than 50 y-o) compared to young/midlife group, but the significance disappeared after partial volume effect (PVE) correction.

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