Gene Expression Changes Accompanying the Duodenal Adenoma-Carcinoma Sequence in Familial Adenomatous Polyposis.

Clin Transl Gastroenterol · 2019 · PMC6613862 · PMID 31211760

Europe PMC DOI

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closest p

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showed a trendno p-value reported

APOA4: PCR analysis verified downregulation in all comparisons; of note, for adenoma-normal, PCR analysis showed a trend toward downregulation.

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did not reach statistical significanceno p-value reported

As a result, PCR comparisons involved lower sample sizes and, while FCs matched our HTA results for 4 candidate genes, P values in some comparisons did not reach statistical significance.

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a trend toward significanceno p-value reported

As in HTA analysis, PCR analysis showed upregulation in cancer-normal and cancer-adenoma, but each comparison had a trend toward significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.