Additionally, p62 (p = 0.05), NDP52 and LC3-II in the heavy membrane (mitochondria-enriched) fraction were lower, although this did not reach statistical significance (Fig. 5D–F ).
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Myocardial hypothermia increases autophagic flux, mitochondrial mass and myocardial function after ischemia-reperfusion injury.
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In addition, diastolic function showed a trend towards improvement, although LAP did not reach statistical significance.