Frequency of self-monitoring of blood glucose in relation to weight loss and A1C during intensive multidisciplinary weight management in patients with type 2 diabetes and obesity.

Although the weak association between SMBG frequency and reduction in A1C did not reach statistical significance in simple linear regression (R 2 =0.18, p=0.06) ( table 4 ), this association was strengthened after adjusting for baseline A1C (adjusted R 2 =0.77, p<0.05) (model 1).

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Although we initially found a weak trend toward better glycemic control with increased frequency of SMBG, the marginal p for trend (0.048) ( table 2 ) mirrored the absence of a statistically significant association in the unadjusted linear regression analysis (p=0.06) ( table 4 ).

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In this cohort, the findings of a strong trend toward higher magnitude of weight loss and reduction in BMI with more frequent SMBG ( table 2 ) were confirmed in multivariate analyses accounting for important confounders including age, sex, baseline BMI, diabetes duration, and use of insulin therapy ( table 3 ).

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