Cumulative asbestos exposure and mortality from asbestos related diseases in a pooled analysis of 21 asbestos cement cohorts in Italy.

A negative trend was observed in men for cardiovascular and for accidental deaths.

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Lung cancer showed a trend similar to pleural MN: mortality was lower than expected in the first 10 years of TSFE, then increased to the highest SMR in the 30–39 year class, followed by a decrease.

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The pattern of mortality from ‘other pneumoconioses’ by tertile of cumulative exposure suggested that at least a proportion of those cases are asbestosis cases: we observed an increasing trend, similar to that observed for the ‘asbestosis’ category but with lower SMRs: I tertile: 1 obs, 1.18 exp., SMR: 0.85 (95% CI: 0.02–4.72); II tertile: 6 obs, 2.46 exp., SMR: 2,44 (95% CI: 0.90–5.31); III tertile: 26 obs, 4.39 exp., SMR: 5.92 (95% CI: 3.87–8.68) (data not tabulated).

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