Abstracts of scientific contributions to GCOM 2019 : Berlin, Germany. 27 - 30 March 2019

BMC Rheumatol · 2019 · PMC6699080

Europe PMC

hedged sentences

0.0920

closest p · 1.8× alpha

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boldest claim

The sentences

marginally significantP < .092so close (0.05 < p ≤ 0.1)

Increasing flare frequency was associated with marginally significant HAQ-DI (F=2.177, P < .092) and significantly greater mean HAQ-Pain (F=13.846, P < .001) as well as more PHQ anxiety (χ2=10.862, P < .012) and depression (χ2=7.061, P < .071). 15.5% reported past year ER/UC use, and 8.6% reported one or more hospital admissions, but neither was associated with flare frequency, perhaps due to the chronic and slowly progressive nature of IBM.

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did not reach statistical significanceno p-value reported

For anti-Jo-1, anti-PM/Scl, anti-Mi-2 and anti-cN1A the trends for HLA association were in the same direction in juvenile-onset IIM as in the combined cohort, but did not reach statistical significance due to small sample numbers.

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showed a trendno p-value reported

Immunocytochemistry showed a trend for upregulated protein-levels of BAFF and CXCL-12 in human myotubes.

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