Association of Tumor Necrosis Factor Alpha, Interleukin 6, and C-Reactive Protein with the Risk of Developing Type 2 Diabetes: A Retrospective Cohort Study of Rural Thais.

J Diabetes Res · 2019 · PMC6702842 · PMID 31485456

Europe PMC DOI

hedged sentences

0.1270

closest p · 2.5× alpha

0.1270

boldest claim

The sentences

a slight trendP = 0.127not close (p > 0.1)

Conversely, the combination of elevated levels of baseline IL-6 and TNF- α was not significantly associated with T2DM; however, subjects in this group showed a slight trend towards increased risk of developing T2DM (OR = 2.34, 95% CI: 0.79-6.97, P = 0.127).

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did not reach statistical significanceno p-value reported

Although it did not reach statistical significance, the T2DM group indicated a trend towards more family members suffering from diabetes.

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a positive trendno p-value reported

Serum CRP correlated significantly with WHR ( r = 0.213, P = 0.001), whereas IL-6 and TNF- α only showed a positive trend towards correlation with WHR ( r = 0.094 and r = 0.123, respectively).

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showed a trendno p-value reported

T2DM risk significantly increased in subjects with high IL-6 levels at both baseline and the first year of reexamination (OR = 4.14, 95% CI: 1.06-16.21), and elevated IL-6 levels for 1 year showed a trend towards increased risk of developing T2DM.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.