Specifically, CeO 2 NPs showed a trend for greater inhibition of lipoperoxidation and ROS production compared to the NAC-treated animals in mice with liver damage 66 , a similar ability to increase GSH compared to NAC in cells under H 2 O 2 -induced oxidative stress 67 , and a stronger protective effect than NAC reducing ROS production and the apoptosis due to the TNF and cycloheximide administration in U937 cells 68 .
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Cerium oxide nanoparticles display antilipogenic effect in rats with non-alcoholic fatty liver disease.
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The PI was higher too, although did not reach statistical significance (1.08 ± 0.14 vs 0.67 ± 0.01 nmol/mg tissue).