Among mothers with PTD, those who experienced PPROM showed a trend toward greater richness when compared to spontaneous PTD cases without PPROM, although the results were not statistically significant (Wilcoxon test, Chao1, P = 0.097) ( Supplementary Figure S3A ).
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Vaginal Microbiome Signature Is Associated With Spontaneous Preterm Delivery.
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gallinarum , BLAST), Atopobium vaginae, Staphylococcus haemolyticus/petrasii , and Bifidobacterium longum were detected as marginally significant before FDR adjustment ( Supplementary Tables S1 , S2 ).
In the present study, we detected a tendency toward increased richness when preterm cases with PPROM were compared with preterm cases who delivered spontaneously without PPROM, but the result did not reach statistical significance.