Overexpression of p16<sup>INK4a</sup> Serves as Prognostic Marker in Squamous Cell Vulvar Cancer Patients Treated With Radiotherapy Irrespective of HPV-Status.

Front Oncol · 2019 · PMC6749023 · PMID 31572682

Europe PMC DOI

hedged sentences

0.0770

closest p · 1.5× alpha

0.0820

boldest claim

The sentences

a strong trendp = 0.077so close (0.05 < p ≤ 0.1)

56.7%, p = 0.033) and a strong trend for better OS (5-year-OS 75.6 vs. 43.9%, p = 0.077).

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showed a trendp = 0.082so close (0.05 < p ≤ 0.1)

Patients with cHPPVC showed a trend for better PFS (5-year-PFS 72.7 vs. 41.3%, p = 0.082) and OS (5-year-OS 81.1 vs. 45.7%, p = 0.084) but no significant benefit for LC.

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