Molecular Imaging of Opioid and Dopamine Systems: Insights Into the Pharmacogenetics of Opioid Use Disorders.

Front Psychiatry · 2019 · PMC6759955 · PMID 31620026

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nominally significantno p-value reported

( 136 ) found a nominally significant association between rs569356 and OUD in a European American population, no significant association was found in Australian and Pakistani populations ( 137 , 273 ).

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did not reach statistical significanceno p-value reported

One [ 11 C]MeNTl PET study found that patients with AUD had slightly greater DOP receptor availability compared to healthy controls in the cingulate, amygdala, insula, ventral striatum, putamen, caudate nucleus, globus pallidus, and thalamus; however, group differences did not reach statistical significance ( 275 ).

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