Maternal Smoking During Pregnancy Induces Persistent Epigenetic Changes Into Adolescence, Independent of Postnatal Smoke Exposure and Is Associated With Cardiometabolic Risk.

Front Genet · 2019 · PMC6764289 · PMID 31616461

Europe PMC DOI

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Dose Dependency With Maternal Smoking: Sensitivity Analysis A sensitivity analysis for dose-dependent methylation with maternal smoking showed a significant trend towards hyper- or hypomethylation with an increasing number in cigarettes consumed (Wilcoxon significance test between groups p < 0.05).

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showed a trendno p-value reported

Additionally, we showed a trend for dose-dependent effects of maternal smoking on offspring CpG methylation levels.

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