The Emerging Role of NANOG as an Early Cancer Risk Biomarker in Patients with Oral Potentially Malignant Disorders.

J Clin Med · 2019 · PMC6780631 · PMID 31484317

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.3890

boldest claim

The sentences

showed a trendp = 0.05actually significant

Nuclear NANOG expression showed a trend to associate with a higher grade of dysplasia (Fisher’s exact test p = 0.05) ( Table 1 ). 3.3.

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almost reached statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

In addition, patients carrying strong cytoplasmic NANOG expression (score 2) experienced a higher progression to OSCC than those with negative to moderate (scores 0 and 1) expression, and these differences almost reached statistical significance (HR = 4.35, 95% CI 0.88 to 22.42; p = 0.07). 3.4.

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did not reach statistical significancep = 0.389not close (p > 0.1)

Positive NANOG expression was associated with a higher 5-year disease-specific survival, although this relationship did not reach statistical significance ( p = 0.389) ( Figure 2 ). 3.5.

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