Pre- and Post-natal High Fat Feeding Differentially Affects the Structure and Integrity of the Neurovascular Unit of 16-Month Old Male and Female Mice.

male mice, but this did not reach statistical significance ( p = 0.06 and p = 0.05, respectively) and no differences were noted between diet groups for either protein ( Figures 2B,C ).

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Comparisons between male and female offspring showed a trend toward increased IgG staining in female mice, which was significantly higher in HF/HF females compared to HF/HF males ( Figure 5A and Supplementary Figure S2B ).

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