Tumor-infiltrating B cells affect the progression of oropharyngeal squamous cell carcinoma via cell-to-cell interactions with CD8<sup>+</sup> T cells.

J Immunother Cancer · 2019 · PMC6796441 · PMID 31623665

Europe PMC DOI

hedged sentence

0.0630

closest p · 1.3× alpha

0.0630

boldest claim

The sentences

a strong trendp = 0.063so close (0.05 < p ≤ 0.1)

did not reach statistical significanceno p-value reported

HPV negativity and high abundance of B cell/CD8 + T cell interactions in the tumor nests did not reach statistical significance, but there was a strong trend ( p = 0.063, HR = 0.29, 95% CI = 0.08–1.06 and p = 0.068, HR = 0.11, 95% CI = 0.01–1.17; respectively).

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