Assessing the genetic association between vitamin B6 metabolism and genetic generalized epilepsy.

Mol Genet Metab Rep · 2019 · PMC6796782 · PMID 31641590

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showed a trendno p-value reported

These polygenic score analyses showed a trend towards lower scores for PLP and PL, but higher scores for PA, PLP:PL and the PAr index in GGE participants ( Fig. 3 ; see Supplementary Table 4 for values).

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nominally significantno p-value reported

Two out of 44 SNPs from the ALPL locus and none from the PYROXD2 locus from the PLP and PLP:PL GWAS showed a nominally significant association with GGE, but these did not survive correction for multiple testing (Supplementary Table 3).

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