Chronic Antibiotic Dependent Pouchitis Is Associated With Older Age at the Time of Ileal Pouch Anal Anastomosis (J-pouch) Surgery.

When age at the time of surgery was evaluated in 5 categories, a significant trend was noted, with increased frequency of CADP as the age at the time of surgery increased (chi-square test of trend, P < 0.001, Fig. 2 ).

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A recent meta-analysis showed a trend toward increased rates of pouchitis in younger individuals although this finding was not significant. 32 The prospective analysis by Chapman et al 31 examined postoperative complications, functional outcomes, and quality of life metrics among individuals who underwent IPAA through annual questionnaires to determine if age at the time of IPAA affected surgical outcomes.

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