The BRCA2 mutation status shapes the immune phenotype of prostate cancer.

Cancer Immunol Immunother · 2019 · PMC6805809 · PMID 31549213

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did not reach statistical significanceno p-value reported

17.2 per HPF, p = 0.59) in the ET1 compartment than in the IT compartment, but differences did not reach statistical significance (Fig. 4 a).

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showed a trendno p-value reported

However, the intratumoral CD8 to FOXP3 ratio showed a trend to be lower in BRCA2 -mutated tumors suggesting a more suppressed tumor immune microenvironment.

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