Thrombelastometry guided blood-component therapy after cardiac surgery: a randomized study.

In this study, there was an overall trend towards improved survival at 30-days, however in the subgroup of “high-risk” patients known to be prone to diffuse coagulopathy a significant reduction in 5-year mortality was proven in the long-term follow-up.

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Overall, there was a strong trend towards less bleeding within the first 24 h in the ROTEM® group visible however not reaching statistical significance ( p = 0.066).

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There was a clear trend towards less 24 h-bleeding visible in the ROTEM® group, also more patients were on coumadin treatment preoperatively and heparin dosages were significantly higher in the ROTEM® group.

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