Barely Significant
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Interleukin-37 Inhibits Colon Carcinogensis During Chronic Colitis.

Front Immunol · 2019 · PMC6857648 · PMID 31781119

Europe PMCDOI
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showed a trendno p-value reported
IL-1β secretion showed a trend in reduction in spontaneous and stimulated whole blood assay of IL10KO/IL37tg mice ( Figure 2B ).

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did not reach statistical significanceno p-value reported
Other pro-inflammatory cytokines as IL-1β, IL-17a, IFNγ, and TNFα were also lower but did not reach statistical significance, indicating that IL-37 contributes to an anti-inflammatory microenvironment within the colon.

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