Simulating Time-Dependent Patterns of Nonadherence by Patients With Breast Cancer to Adjuvant Oral Endocrine Therapy.

JCO Clin Cancer Inform · 2019 · PMC6873985 · PMID 31002563

Europe PMC DOI

hedged sentences

0.1000

closest p · 2.0× alpha

0.2900

boldest claim

The sentences

approached significanceP < .10so close (0.05 < p ≤ 0.1)

However, five reasons approached significance, with P < .10, including weight gain ( P = .07), cognitive dysfunction ( P = .06), worry about ET cost ( P = .07), general dislike of taking medication ( P = .07), and forgetting to take medication ( P = .07), meaning that these reasons displayed a ≤ 7% chance of being a random sequence ( Fig 4 ).

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a strong trendP = 0.29not close (p > 0.1)

Conversely, insomnia, bone and joint pain, hot flashes, worry about bone loss, vaginal dryness, emotional distress, decreased sex drive, and worry about ET interaction with other prescribed medications did not show a strong trend across time ( P = 0.29 to 1.00) and thus exercised relatively stable influences on nonadherence during the first 6 years of ET.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.