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Troubleshooting in Large-Scale LC-ToF-MS Metabolomics Analysis: Solving Complex Issues in Big Cohorts.

Metabolites · 2019 · PMC6918290 · PMID 31652940

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showed a trendno p-value reported
Moreover, from the IS compounds that eluted at the beginning of the chromatogram, L-carnitine-D 3 showed a trend to decrease the signal and such trend was not observed in isoleucine 13 C, 15 N.

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a clear trendno p-value reported
Regarding the normalization by IS mix, TUS plots for both modes showed a clear trend to increase the signal along the injection order.

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