Complex interrelationships between nitro-alkene-dependent inhibition of soluble epoxide hydrolase, inflammation and tumor growth.

Although, this analysis did not identify any statistical differences between experimental interventions, it was notable that the WT mice exposed to nitro-oleate showed a trend for increased ratios of plasma 14(15)-, 11(12)- and 8(9)-EET/DHET.

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For example, although there was a trend for the nitro-oleate to increase the plasma EET/DHET ratio for the regioisomer pairs measured, this did not reach statistical significance.

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