Whole Exome Sequencing Study of Parkinson Disease and Related Endophenotypes in the Italian Population.

Front Neurol · 2019 · PMC6965311 · PMID 31998221

Europe PMC DOI

hedged sentences

0.0330

closest p · 0.7× alpha

0.0330

boldest claim

The sentences

nominally significantp = 0.033actually significant

Similarly, rs3835072 showed the most significant multivariate association with the different PD endophenotypes tested ( p = 1.88 × 10 −6 ), supported by a nominally significant effect on UPDRS ( p = 0.033, β (SE) = −0.038 (0.017)], in addition to the one detected with MoCA.

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approached significanceno p-value reported

However, this association only approached significance in an extended follow-up analysis of our PD cohort, which does not support a significant influence of this gene on cognitive performance.

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