The association between genome-wide polymorphisms and chronic postoperative pain: a prospective observational study.

Anaesthesia · 2020 · PMC6973279 · PMID 31903573

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0680

boldest claim

The sentences

nominally significantp < 0.05actually significant

Several nominally significant associations were found (rs11655475 and rs4790802, p < 0.05) but these were not annotated to a gene.

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showed a trendp = 0.068so close (0.05 < p ≤ 0.1)

The SNP (rs118184265) in NAV3 showed nominal significance (p < 0.01) with chronic postoperative pain at 3 months and two SNPs within RSU1 (rs7894047, rs7893777) showed a trend towards statistical significance (p = 0.068).

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