Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer's disease.

Hippocampal X34 plaque burden did not reach statistical significance in 5XFAD/RKO mice due to a single mouse, but it was a strong trend toward a decrease in that region (Figure 6 d).

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