N-Acetylcysteine causes analgesia in a mouse model of painful diabetic neuropathy.

Mol Pain · 2020 · PMC6997966 · PMID 32009537

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did not reach statistical significanceno p-value reported

69 PD0325901 caused analgesia in diabetic mice, although the increase in mechanical pain thresholds did not reach statistical significance.

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showed a trendno p-value reported

Interestingly, NAC treatment reduced MAP kinase activation and showed a trend to a reduction in P2X7 receptor expression in the dorsal regions of the spinal cord of both control and STZ-treated mice.

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