Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence.

Nutrients · 2020 · PMC7019700 · PMID 31963141

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failed to reach statistical significanceno p-value reported

Benefits on depressive symptoms failed to reach statistical significance, but conclusions were stronger for stress.

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showed a trendno p-value reported

Several studies using functional biomarkers of vitamin B12 status showed a trend towards associations between poor vitamin B12 status in an ageing population and faster cognitive decline and risk of Alzheimer’s disease [ 169 ].

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highly significantno p-value reported

This study revealed a highly significant treatment effect of iron on fatigue, with an overall decrease of fatigue complaints of more than 60% [ 128 ].

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