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To Feed or Not to Feed: A Critical Overview of Enteral Feeding Management and Gastrointestinal Complications in Preterm Neonates with a Patent Ductus Arteriosus.

Nutrients · 2019 · PMC7019993 · PMID 31892190

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Continuous infusion of intravenous ibuprofen was associated with the lowest NEC incidence, whereas standard or high doses of intravenous ibuprofen and standard doses of intravenous indomethacin ranked worse than placebo or no treatment, but these differences failed to reach statistical significance [ 23 ]. 3.2.

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Lower SMA–BFVs in the large PDA group were also observed 60 min after the administration of a small test feed; however, the between-group comparison did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.