Prospective examination of synthetic 5-methoxy-N,N-dimethyltryptamine inhalation: effects on salivary IL-6, cortisol levels, affect, and non-judgment.

Psychopharmacology (Berl) · 2020 · PMC7036074 · PMID 31822925

Europe PMC DOI

hedged sentences

0.0680

closest p · 1.4× alpha

0.0730

boldest claim

The sentences

approaching significancep = .068so close (0.05 < p ≤ 0.1)

Subjective measures of affect and cognition Overall, main effects of session reached significance on anxiety (as assessed by DASS-21) ( F 2, 19.380 = 6.023; p = .009, η p 2 = 0.38), eta = .551), depression (as assessed by DASS-21) ( F 2, 9.979 = 8.104; p = .008, η p 2 = 0.18), and non-judgment (as assessed by FFMQ) ( F 2, 10.182 = 14.018; p = .001, η p 2 = 0.45), while approaching significance in stress (as assessed by DASS-21) ( F 2, 20.355 = 3.070; p = .068, η p 2 = 0.21), see Fig. 3 .

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approached significancep = .073so close (0.05 < p ≤ 0.1)

Moreover, there was a reduction in depression ratings which approached significance at 7-day follow-up ( p = .073, Hedges’ g = 0.30).

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