Plasma ubiquitin C-terminal hydrolase L1 levels reflect disease stage and motor severity in Parkinson's disease.

Aging (Albany NY) · 2020 · PMC7053593 · PMID 31932518

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hedged sentences

0.0560

closest p · 1.1× alpha

0.0560

boldest claim

The sentences

did not reach statistical significancep=0.056so close (0.05 < p ≤ 0.1)

Although these results did not reach statistical significance, there was a near- significant trend in the PD group (p=0.056) that warrants further investigation in a larger sample size.

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a near-significant trendp = 0.056so close (0.05 < p ≤ 0.1)

In the PD group, there was a near-significant trend towards higher UCHL1 levels in carriers of long SNCA Rep1 alleles vs short alleles (5.21 vs 3.71 pg/ml, p = 0.056, Figure 2 ), while a non-significant trend was seen in healthy controls carrying long Rep1 vs short alleles (3.39 vs 1.42 pg/ml, p = 0.207), adjusted for age and gender, and disease duration in the PD group.

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