Rituximab Prevents the Development of Experimental Autoimmune Encephalomyelitis (EAE): Comparison with Prophylactic, Therapeutic or Combinational Regimens.

J Inflamm Res · 2020 · PMC7082624 · PMID 32214838

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

did not reach statistical significanceP = 0.0540so close (0.05 < p ≤ 0.1)

Although there was a trend in reducing the clinical score, this did not reach statistical significance when compared to untreated group (P = 0.0540, Figure 3A ).

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showed a trendno p-value reported

Comparison of the EAE clinical score among untreated mice (gray line) and mice treated with 5 μg RTX IP therapeutically (blue line) showed a trend of ameliorating the clinical score but there was no statistically significant difference in EAE clinical score among untreated group and IP therapeutic RTX-treated group ( Figure 4A ).

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