8q24 genetic variation and comprehensive haplotypes altering familial risk of prostate cancer.

Nat Commun · 2020 · PMC7089954 · PMID 32251286

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.1000

boldest claim

The sentences

nominally significantP ≤ 0.05actually significant

In total, 433 of the 765 (57%) were concordantly nominally significant in the NFPCS under additive models ( P ≤ 0.05, Supplementary Fig. 1 and Supplementary Data File 1 ) .

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approached significanceP < 0.1so close (0.05 < p ≤ 0.1)

Two variants of moderate-risk haplotype B were associated with an earlier age of diagnosis among HPC cases (rs7005144_ A , P = 0.023, and rs191785584_ G , P = 0.019), but nearly all other variants marking this haplotype also approached significance ( P < 0.1).

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