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Multivariate analysis showed patients’ age, positive endocervical and overall excision margins and worse definitive histological diagnosis (high grade cervical intraepithelial neoplasia or invasive carcinoma) to be statistically significant (p < 0.001) in predicting higher recurrence/persistence rate, whereas positive ectocervical excision margin was not quite statistically significant (p = 0.0447) and cone depth was not statistically significant at all (p = 0.181).

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This differences are almost significant (p = 0.0565).

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In bi-variate Cox regression analysis, CR/IDC (HR 3.3; 95 % CI 1.4–8.0; P = .008) was an independent parameter for disease-specific death, while %GG4 (HR 1.5; 95 % CI 1.0–2.4; P = .06) did not reach statistical significance.

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Non-significant differences were found between the two subgroups with respect to 6-year mortality and major aorta related events, although the mixed group showed a trend to a poorer prognosis.

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of Pathology, Bucharest, Romania Objective: Endometrial carcinoma is the 4th most common malignancy of the female reproductive system in Romania which is currently recording an increasing trend worldwide as well as in our country.

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