9p21.3 coronary artery disease risk locus and interferon alpha 21: Association study in an Asian Indian population.

SNPstat analysis revealed that the TT and TC genotypes of rs10757272 showed a significant risk association among female CAD patients (OR = 8.15 for TC and 9.27 for TT, p = 0.012 in the codominant model), CC genotype of rs1333045 showed a significant risk association among all CAD patients (OR = 1.46, p = 0.046 in the recessive model), CC genotype of rs1333049 showed a trend toward risk association among premature (age at presentation < 55 years in males and <65 years in females) CAD patients (OR = 1.61, p = 0.061 in the recessive model), and GG genotype of rs4977574 showed a significant risk association among premature CAD patients (OR = 1.77, p = 0.025 in the recessive model).

also in 53,322 other papers

• Age: Among controls, there is a higher proportion of individuals in the high-level IFNA21 group in both the age categories (<50 years and ≥50 years), with the p -value approaching significance ( p = 0.064).

also in 2,640 other papers