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Cotinine Enhances Fear Extinction and Astrocyte Survival by Mechanisms Involving the Nicotinic Acetylcholine Receptors Signaling.

Front Pharmacol · 2020 · PMC7142247 · PMID 32300297

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showed a trendno p-value reported
In the extinction trials, mice treated with cotinine plus DHβE showed a trend of reduced retention of fear memory when compared to mice treated with cotinine alone but the difference did not reach statistical significance respect to conditioned mice treated with cotinine alone.

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