Prenatal androgen induced lean PCOS impairs mitochondria and mRNA profiles in oocytes.

Endocr Connect · 2020 · PMC7159265 · PMID 32101528

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showed a trendno p-value reported

Mitochondrial genes mtNd4l, mtNd5, mtAtp6 and mtRnr1 as well as nuclear genes Gja1 and Sfrp4 showed similar expression in both controls and lean PCOS groups, and Xrcc1 showed a trend in lower abundance that did not reach statistical significance (Data not shown).

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did not reach statistical significanceno p-value reported

The mitochondrial genes mtNd2, mtNd3, mtNd4, mtCytb, mtAtp8 and mtRnr2 in addition to the nuclear genes Opa1, Mfn2, Ect2, Atrx, Cep70, Tacc1, Pcm1, Gdf9, Nobox, Zmic1, Kat2b, Ppp2r1a and Ppp2ca all showed a tendency to be more abundant; however, did not reach statistical significance.

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