Vitamin D Receptor Overexpression in β-Cells Ameliorates Diabetes in Mice.

2 B ) revealed a nonsignificant trend toward a reduction in the expression levels of VDR and SLC2A2 in islets from T2D patients.

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In contrast, Gcg expression was unaltered, and Ucp2 expression presented a clear trend to increase in STZ islets ( Fig. 1 D ).

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It is noteworthy that our results obtained from publicly available data sets also showed a trend toward a reduction in VDR expression in human islets from T2D patients.

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