Prospective registration and reporting of trial number in randomised clinical trials: global cross sectional study of the adoption of ICMJE and Declaration of Helsinki recommendations.

BMJ · 2020 · PMC7190012 · PMID 32291261

Europe PMC DOI

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a clear trendno p-value reported

A clear trend was observed for a higher number of trials registering in the early weeks after enrolment.

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a trend towards significanceno p-value reported

did not reach statistical significanceno p-value reported

The odds of prospective trial registration showed a trend towards significance for industry funded trials, with a 2.5 times greater likelihood of trial being registered prospectively before enrolment; however, the trend did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.