Barely Significant
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Impact of Interferon-Based Treatment on Quality of Life and Work-Related Productivity of Korean Patients with Chronic Hepatitis C.

Gut Liver · 2020 · PMC7234875 · PMID 31533395

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showed a trendno p-value reported
After treatment initiation, IFN-treated patients showed a trend towards deterioration of both general (baseline: 0.87±0.103, week 4: 0.77±0.153) and HCV-specific (baseline: 76.2±19.5, week 4: 68.2±22.3) HRQoL.

also in 53,322 other papers

a clear trendno p-value reported
DISCUSSION Probably the most crucial result observed in Korean patients with a HCV infection initiating IFN-based treatment was a clear trend for decreased QoL and productivity following treatment initiation.

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a slight trendno p-value reported
Health-related QoL After treatment initiation, IFN-treated patients showed a slight trend for deterioration of both general and HCV-specific HRQoL, measured using EuroQoL 5-dimension 5-level (EQ-5D-5L) and HCV patient-reported outcomes (HCV-PRO), respectively.

also in 4,078 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.