Effect of a sepsis prediction algorithm on patient mortality, length of stay and readmission: a prospective multicentre clinical outcomes evaluation of real-world patient data from US hospitals.

68 Austrian et al performed a time-series study which evaluated an electronic surveillance system on mortality and LOS on emergency department patients with severe sepsis or septic shock, 69 finding a modest decrease in LOS (16%) that did not reach statistical significance, with no difference in-hospital mortality or other intermediate outcome measures.

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However, additional outcome measures of hospital LOS (p=0.92), ICU transfer <24 hours after alert (p=0.20), renal replacement therapy ≤6 hours after alert (p=0.51) and all-patient mortality reductions (p=0.45) failed to reach statistical significance. 68 Austrian et al performed a time-series study which evaluated an electronic surveillance system on mortality and LOS on emergency department patients with severe sepsis or septic shock, 69 finding a modest decrease in LOS (16%) that did not reach statistical significance, with no difference in-hospital mortality or other intermediate outcome measures.

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