Current intensity- and polarity-specific online and aftereffects of transcranial direct current stimulation: An fMRI study.

Hum Brain Mapp · 2020 · PMC7267945 · PMID 31860160

Europe PMC DOI

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0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

marginally nonsignificantp = .060so close (0.05 < p ≤ 0.1)

Cathodal‐M1 tDCS An ANOVA of the mean CBF differences in the targeted left motor hand knob area showed a marginally nonsignificant main effect of intensity ( F (4,52) = 2.415, p = .060, ηp 2 = .157), a significant effect of time ( F [4.320,56.164] = 12.944, p = <.001, ηp 2 = 0.499) and a significant intensity × time interaction ( F [32,416] = 1.943, p = .002, ηp 2 = 0.130).

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a small trendno p-value reported

However, there was a small trend whereby an individual's M1 gray matter volume tended to correlate with efficacy of 2.0 mA anodal‐M1 tDCS.

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showed a trendno p-value reported

In follow‐up post‐hoc tests, all active intensities showed a trend of decreased CBF in the targeted left M1 area (Figure 3 h).

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did not reach statistical significanceno p-value reported

Positive trend‐wise associations between increased CBF as a function of increased excitability were also observed with the 0.5 and 2.0 mA intensities in this ROI, although these correlations did not reach statistical significance.

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