The pheta1 heterozygous ( pheta1 +/− ) and homozygous ( pheta1 −/− ) animals showed a trend of reduced tracer uptake, compared to the WT control animals, but the difference did not reach statistical significance ( Fig. 3 B) (Chi-square test; sample sizes are shown in the figure).
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Deficiency in the endocytic adaptor proteins PHETA1/2 impairs renal and craniofacial development.
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